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allophycocyanin cy7 anti cd4  (Cytek Biosciences)


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    Cytek Biosciences allophycocyanin cy7 anti cd4
    Allophycocyanin Cy7 Anti Cd4, supplied by Cytek Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/allophycocyanin cy7 anti cd4/product/Cytek Biosciences
    Average 93 stars, based on 10 article reviews
    allophycocyanin cy7 anti cd4 - by Bioz Stars, 2026-05
    93/100 stars

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    Interleukin (IL)-7 promotes differentiation toward memory and effector T cells and cytokine-secreting T-helper cells . The number of naive CD4 T cells (CD44-CD62L + ) was not significantly altered by IL-7. By contrast, a significant increase in central memory (CD44 + CD62L + ) and effector memory (CD44 + CD62L - ) T cells was found after IL-7 administration (A) . IL-7 enhances numbers (and percentages) of CD4 T cells, and of Th1 (interferon (IFN)-g)-, and Th17 (IL-17)-, and Th2 (IL-4)-cytokine-secreting CD4 T cells (B) . Increased IFN-g was measured in supernatants from lymph node cells (LNs) of the IL-7-treated mice as compared with those of the PBS-treated mice. Moreover, on collagen type II (CII) restimulation of LNs, increased IL-17 and reduced IL-4 concentrations were measured, as compared with those of PBS-treated mice (C) . Statistical differences with PBS group of * P < 0.05, ** P < 0.01, and *** P < 0.001.

    Journal: Arthritis Research & Therapy

    Article Title: Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation

    doi: 10.1186/ar3870

    Figure Lengend Snippet: Interleukin (IL)-7 promotes differentiation toward memory and effector T cells and cytokine-secreting T-helper cells . The number of naive CD4 T cells (CD44-CD62L + ) was not significantly altered by IL-7. By contrast, a significant increase in central memory (CD44 + CD62L + ) and effector memory (CD44 + CD62L - ) T cells was found after IL-7 administration (A) . IL-7 enhances numbers (and percentages) of CD4 T cells, and of Th1 (interferon (IFN)-g)-, and Th17 (IL-17)-, and Th2 (IL-4)-cytokine-secreting CD4 T cells (B) . Increased IFN-g was measured in supernatants from lymph node cells (LNs) of the IL-7-treated mice as compared with those of the PBS-treated mice. Moreover, on collagen type II (CII) restimulation of LNs, increased IL-17 and reduced IL-4 concentrations were measured, as compared with those of PBS-treated mice (C) . Statistical differences with PBS group of * P < 0.05, ** P < 0.01, and *** P < 0.001.

    Article Snippet: For flow-cytometric analysis, monoclonal antibodies were used: anti-CD4 allophycocyanin (APC)/Cy7 (clone-Gk1.5; BD), anti-CD8 Pacific Blue (PB) (clone-53-6.7; BD), anti-CD19 peridinin-chlorophyll-protein (PerCP)/Cy5.5 (clone-1D3; BD), anti-CD44 FITC (clone-IM7; eBioscience, San Diego, CA, USA), and anti-CD62L APC (clone-mel-14; BD).

    Techniques: